The association between heart rate variability and daily profile of blood pressure in patients with essential hypertension

А.Г. Полупанов, Н.Б. Ческидова, Т.А. Романова, А.С. Джумагулова

Authors: A.G. Polupanov, N.B. cheskidova, T.A. Romanova, A.S. Dzhumagulova

Place: Bishkek, Kyrgyzstan

Institution: National Centre of Cardiology and Internal Medicine named after M. Mirrahimov

Abstract:

Objective. To study the correlation of heart rate variability with daily profile of blood pressure (BP) in patients with essential hypertension (EH). Design and methods. We examined 61 male with uncomplicated EH, aged 30-65 years (mean age 45,2 ± 7,6 years). We used spectral analysis at rest and during the functional tests (active tilt-test) to study the heart rate variability, and we performed ambulatory BP monitoring (ABPM). Based on the ABPM data, all patients were divided into 3 groups. The first group included 26 patients with normal nocturnal BP decline (10-20 % — dippers). The second group included 28 patients with insufficient nocturnal BP decline ( 20 % — over-dippers). Results. The most of the patients showed relatively normal autonomic heart regulation and were classified as dippers and over-dippers. Non-dippers demonstrated a reduction of sympathetic nervous system adaptive capabilities that was reflected by the decrease of LF-component against the normal reaction of HF-modulations. Conclusions. The changes of daily BP profile in EH patients may be associated with the baroreflex failure reflected by the disadaptation reactions of HRV LF-component at tilt-test.

Keywords: essential hypertension, heart rate variability, ambulatory blood pressure monitoring

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