Association between arterial stiffness and cardiovascular remodeling depending on blood pressure level

О.Ю. Бастриков, Е.А. Григоричева, В.В. Белов

Authors: O.Yu. Bastrikov, E.A. Grigoricheva, V.V. Belov

Place: Chelyabinsk, Russia

Institution: South Ural State Medical University

Abstract: Objective. To study the indices of local arterial stiffness in correlation with structure-functional parameters of cardiovascular remodeling in healthy individuals and in hypertensive patients. Design and methods. We carried out a cross-sectional population study in workers of an industrial enterprise. Altogether 213 people were enrolled, including 106 patients with arterial hypertension stage I–II and 107 healthy individuals. We assessed the stage and the grade of hypertension together with the additional categories of cardiovascular risk in accordance with national guidelines. All patients underwent echocardiography, ultrasound of the carotid arteries with simultaneous evaluation of arterial stiffness. Results. Hypertensive patients demonstrated a significant association between arterial stiffness indices and intima-media thickness (91 %) and echocardiographic parameters of the left heart volume. Conclusion. The indices of arterial stiffness may serve as markers of effective management of risk factors in individuals with normal blood pressure and those of drug therapy in hypertensive patients.

Keywords: arterial stiffness, cardiovascular remodeling, arterial hypertension

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