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Systemic disorders of inorganic phosphate exchange as a novel cluster of cardiovascular risk factors

В. А. Добронравов

Authors: V. A. Dobronravov

Place: St Petersburg, Russia

Institution: First Pavlov State Medical University of St. Petersburg, St Petersburg, Russia

Abstract: Recent studies have clearly linked higher serum inorganic phosphate (Pi) concentrations and an imbalance of Pi-regulation by kidney-bone-parathyroid endocrine systems to cardiovascular events and mortality. This association has been identified in patients with chronic kidney disease, as well as in general population. The editorial discusses the available clinical and experimental data linking the pathophysiology of phosphate exchange disorders and cardiovascular events.

Keywords: inorganic phosphate, chronic kidney disease, cardiovascular diseases, cardiovascular risks

 

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