Circadian blood pressure profile in patients with chronic cardiorenal syndrome

В. А. Серов, А. М. Шутов, Д. В. Серова, С. В. Шевченко, Е. Ю. Шмелькова

Authors: V. A. Serov 1, A. M. Shutov 1, D. V. Serova 1, S. V. Shevchenko 2, E. U. Shmelkova 2

Place: Ulyanovsk, Russia

Institution: 1 Ulyanovsk State University
2 Ulyanovsk Central City Hospital

Abstract: Objective. To determine the features of circadian blood pressure (BP) profile depending on renal function in patients with chronic heart failure (CHF). Design and methods. We examined 211 patients with CHF (126 men and 85 women), including 125 (59,2 %) patients with cardiorenal syndrome and 86 (40,8 %) patients without chronic kidney disease (CKD). Mean age was 58,1 ± 10,8 years. CKD was diagnosed according to the Scientific Society of Russian Nephrologists guidelines 2012. Results. An increase in time and area indices of arterial hypotension in patients with CHF, associated with CKD 3B stage was detected. Also, the nocturnal BP fall reduction was associated with increasing severity of CKD. conclusions. 1. The increase in nocturnal BP fall is associated with increasing in daytime area and time indices of arterial hypotension in patients with cardiorenal syndrome. 2. Twenty-four-hour ambulatory BP monitoring allows to obtain additional information on hemodynamic parameters in patients with CHF and should be recommended for this group of patients.

Keywords: chronic heart failure, chronic kidney disease, twenty-four-hour ambulatory blood pressure monitoring

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